A drop in insulin production in your brain may contribute to the degeneration of your brain cells, and studies have found that people with lower levels of insulin and insulin receptors in their brain often have Alzheimer's disease. Researchers have now discovered that insulin does far more than simply regulating blood sugar. Your brain does not require glucose, and actually functions better burning alternative fuels, especially ketones. In fact, Dr. Rosedale believes that it is the constant burning by the brain of glucose that is primarily to blame for Alzheimer's and other brain disorders
Insulin is actually a "master multitasker" that helps with neuron glucose-uptake, and the regulation of neurotransmitters, like acetylcholine, which are crucial for memory and learning. This is why reducing the level of insulin in your brain impairs your cognition. Other research11 shows that type 2 diabetics lose more brain volume with age than expected—particularly gray matter. This kind of brain atrophy is yet another contributing factor for dementia. "Brain diabetes" may also be responsible for glaucoma, according to recent research. As reported by Medical News Today:12
"Researchers [in India]... have proposed a new mechanism of glaucoma which suggests that diabetes can occur in the brain and may be the cause of many neurodegenerative disorders including glaucoma... an irreversibly blinding disorder with almost 65 million sufferers worldwide. There is no cure...
The recent paper titled 'Glaucoma: Diabetes of the brain - a radical hypothesis about its nature and pathogenesis', published in Medical Hypotheses... explore glaucoma and related neurodegenerative diseases from many perspectives and come up with a multifaceted and internally coherent concept of glaucoma being 'the diabetes of the brain.'"
It's becoming increasingly clear that the same pathological process that leads to insulin resistance and type 2 diabetes may also hold true for your brain. As you over-indulge on sugar and grains, your brain becomes overwhelmed by the consistently high levels of glucose and insulin that blunts its insulin signalling, leading to impairments in your thinking and memory abilities, eventually causing permanent brain damage.
Additionally, when your liver is busy processing fructose (which your liver turns into fat), it severely hampers its ability to make cholesterol, an essential building block of your brain that is crucial for optimal brain function. Indeed, mounting evidence supports the notion that significantly reducing fructose consumption is a very important step you can take to prevent Alzheimer's disease.